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Urethane adhesives are different from urethane sealants in that the two-part formulations react when mixed and do not require moisture to cure. Urethan adhesives remain flexible when cured, making them the ideal choice for impact and vibration-resistant adhesives. They also bond extremely well to most plastics, wood, concrete, and rubber. The high-impact flexibility makes urethane adhesives a great option for bonding dissimilar substrates.